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Ivermectin is one of the drugs that showed a positive response in labs earlier this year for treating SARS CoV-2, the virus that causes COVID-19.
San Antonio doctor uses this medicine to treat COVID patients. "It prevents COVID from replicating," Dr. Hoan Pho said of Ivermetcin. "And it also decreases the viral load." "Using ivermectin so far has helped the patients get better and quicker and preventing them from getting pneumonia," he said. (from www.cbs19.tv / Published: 9:59 PM CST January 5, 2021)

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KENS-TV San Antonio logoSan Antonio doctor uses hair lice medicine to treat COVID-19 patients; FDA warns more testing is needed
As hospitalizations surge in Bexar County, one San Antonio doctor is using a head lice drug that he believes is keeping his COVID-19 patients from ending up in the hospital.
Ivermectin is considered to be a safe drug to treat different types of parasitic infections in humans and animals, including lice, but is not FDA-approved for other uses.
However, Dr. Hoan Pho said when ivermectin is combined with other drugs, this medicine is working to treat his patients who have contracted COVID-19.
The FDA recognizes ivermectin has shown some effectiveness in a laboratory setting, but additional testing is needed, as the results from trials are still limited, according to the agency's website.
What is ivermectin and what does FDA think about it as a possible COVID-19 treatment?
Pho specializes in internal medicine and cites a study suggesting that the anti-parasitic drug can kill the coronavirus within 48 hours in a lab setting.
"It prevents COVID from replicating," he said. "And it also decreases the viral load."
The drug is widely available and runs about $20. Within the last month, Dr. Pho started using the drug on his patients.
"About 50-60 patients, there is no hospitalization," he said. "Nobody has gotten sicker and has required oxygen to be hospitalized."
He said half those patients were over the age of 65. If a patient is sick with COVID, Pho prescribes ivermectin with a couple of other drugs and supplements. He does believe the key is ivermectin.
"Using all of these medicines, particularly the ivermectin, so far has helped the patients get better quicker and preventing them from getting pneumonia," he said.
Indonesian Institute of Sciences (LIPI),Wonosari 55861, Indonesia; andri.frediansyah@lipi.go.id7Department of Pharmaceutical Biology, Pharmaceutical Institute, University of Tübingen,72076 Tübingen, Germany8Department of Microbiology and Parasitology, Faculty of Medicine and Health Sciences,Warmadewa University, Denpasar 80239, Indonesia; amegawati@ucdavis.edu
To respond to the pandemic, a long list of potential drugs hasbeen proposed as potential treatments for COVID-19; some of these have been selected for clinical trialsin many countries [7,8]. In accordance with the concept of drug repurposing, these prospective drugs,which are either already marketed as antivirals or have been chosen from different pharmacologicalclasses, have been suggested to provide antiviral activity against SARS-CoV-2
Over the past three decades, approximately 3.7 billion doses of ivermectin have beendistributed worldwide through mass drug administration (MDA) campaigns [26].Ivermectin isavailable in multiple forms, including tablets, capsules, and an oral solution; however, it isonly approved for administration via the oral route for humans. Studies of the metabolism of ivermectinin humans are limited; however, it was suggested that the drug is extensively metabolized in the liver [25].
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In PRV, ivermectin inhibited viral entrance into thecell nucleus,as well asviral proliferation, in a dose-dependent manner [29]. The drug significantlyreduced viral DNA synthesis, inhibited virus production, and blocked DNA polymerase accessorysubunit UL42 entrance into the nucleus by targeting the nuclear localization signal in the transfectedcells [29]. ivermectin buy near me
Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis,California, CA 95616, USA10Department of Parasitology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh 23111, Indonesia11Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh 243122,India; kdhama@rediffmail.com*Correspondence: mudatsir@unsyiah.ac.id (M.M.); harapan@unsyiah.ac.id (H.H.)Received: 20 July 2020; Accepted: 10 August 2020; Published: 17 August 2020 ivermectin cream buy uk
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Ivermectin is an antiparasitic drug that has shown also an effective pharmacological activity towards various infective agents, including viruses. This paper proposes an alternative mechanism of action for this drug that makes it capable of having an antiviral action, also against the novel coronavirus, in addition to the processes already reported in literature.
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