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Ivermectin is one of the drugs that showed a positive response in labs earlier this year for treating SARS CoV-2, the virus that causes COVID-19.
San Antonio doctor uses this medicine to treat COVID patients. "It prevents COVID from replicating," Dr. Hoan Pho said of Ivermetcin. "And it also decreases the viral load." "Using ivermectin so far has helped the patients get better and quicker and preventing them from getting pneumonia," he said. (from www.cbs19.tv / Published: 9:59 PM CST January 5, 2021)



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KENS-TV San Antonio logoSan Antonio doctor uses hair lice medicine to treat COVID-19 patients; FDA warns more testing is needed
As hospitalizations surge in Bexar County, one San Antonio doctor is using a head lice drug that he believes is keeping his COVID-19 patients from ending up in the hospital.
Ivermectin is considered to be a safe drug to treat different types of parasitic infections in humans and animals, including lice, but is not FDA-approved for other uses.
However, Dr. Hoan Pho said when ivermectin is combined with other drugs, this medicine is working to treat his patients who have contracted COVID-19.
The FDA recognizes ivermectin has shown some effectiveness in a laboratory setting, but additional testing is needed, as the results from trials are still limited, according to the agency's website.
What is ivermectin and what does FDA think about it as a possible COVID-19 treatment?
Pho specializes in internal medicine and cites a study suggesting that the anti-parasitic drug can kill the coronavirus within 48 hours in a lab setting.
"It prevents COVID from replicating," he said. "And it also decreases the viral load."
The drug is widely available and runs about $20. Within the last month, Dr. Pho started using the drug on his patients.
"About 50-60 patients, there is no hospitalization," he said. "Nobody has gotten sicker and has required oxygen to be hospitalized."
He said half those patients were over the age of 65. If a patient is sick with COVID, Pho prescribes ivermectin with a couple of other drugs and supplements. He does believe the key is ivermectin.
"Using all of these medicines, particularly the ivermectin, so far has helped the patients get better quicker and preventing them from getting pneumonia," he said.
Ivermectin: An Introduction. Ivermectin is an antiparasitic agent with broad spectrum activity, high efficacy, and a wide safetymargin. It has been in common use in veterinary medicine since 1981 for the treatment of onchocerciasisand filariasis [24]. Ivermectin was first used in humans in 1987 for the treatment of onchocerciasis;currently, it is approved in many countries for the treatment of onchocerciasis, filariasis, strongyloidiasis,and scabies [25].
Ivermectin and SARS-CoV-2 InfectionThere are no antiviral drugs available to treat SARS-CoV-2 infection. However, several clinicaltrials are in progress to explore the potential antiviral activities of some drugs. Although most of thesedrugs were initially designed for other pathogens, they appear to have the potential to treat COVID-19,either by acting directly on the virus or modulating the human immune system [30].
A previous study suggested an antagonistic effect of ivermectin on vitamin K after hematomatousswellings were reported in two out of 28 ivermectin-treated patients, along with a significantly increasedprothrombin time of between 1 week and 1 month after drug administration [28]. Notably, even thoughthe reduction of factor II and factor VII levels was reported to occur in most of the patients, bleedingcomplications were not observed in any patients [28].
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In PRV, ivermectin inhibited viral entrance into thecell nucleus,as well asviral proliferation, in a dose-dependent manner [29]. The drug significantlyreduced viral DNA synthesis, inhibited virus production, and blocked DNA polymerase accessorysubunit UL42 entrance into the nucleus by targeting the nuclear localization signal in the transfectedcells [29]. ivermectin for sale uk
West Nile virus [21], and Venezuelan equine encephalitis virus [22].An initialin vitrostudy suggested that ivermectin could inhibit SARS-CoV-2 [23]. In this review,we have summarized the evidence from docking and modeling studies,in vitroandin vivostudies,new investigational drug protocols, and, where available, clinical trials; from this evidence, we aim toevaluate the potency of ivermectin for use as a treatment option for COVID-19.2. ivermectin buy canada
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This review has summarized the evidencederived from docking and modeling analysis,in vitroandin vivostudies, and results from newinvestigational drug protocols, as well as clinical trials, if available, which will be effective insupporting the prospective use of ivermectin as an alternative treatment for COVID-19.Keywords: SARS-CoV-2; COVID-19; ivermectin; treatment; antiviral1. IntroductionIn December 2019, the novel coronavirus disease 2019 (COVID-19), caused by severe acuterespiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in central China [1,2].
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